HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-1,3-thiazol-4-amine → 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid (2-methyl-thiazol-4-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-1,3-thiazol-4-amine | HCID 14772700 | — |
| Reactant | 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid ethyl ester | HCID 69237299 | — |
| Product | 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid (2-methyl-thiazol-4-yl)-amide | HCID 11587936 | — |
Reaction Steps
The title compound, was prepared from 6-Methyl-3-(2-methyl-2H-pyrazol-3-ylamino)-pyridine-2-carboxylic acid ethyl ester in accordance with the general method of example 75, step 2 using 4-Amino-2-methylthiazole instead of 3-Amino-1-methyl-pyrazole to yield the final compound as a light brown solid, MS (ISP): m/e=329.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-d1c072b7d00d4a21bdd9df8cdb167405 |
| Source note | uspto-grants-2008_08 |