HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-1,3-thiazol-4-amine → 3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid (2-methyl-thiazol-4-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-1,3-thiazol-4-amine | HCID 14772700 | — |
| Reactant | 3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid ethyl ester | HCID 69236417 | — |
| Product | 3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid (2-methyl-thiazol-4-yl)-amide | HCID 11602591 | — |
Reaction Steps
The title compound, was prepared from 3-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-6-methyl-pyridine-2-carboxylic acid ethyl ester and 4-Amino-2-methylthiazole in accordance with the general method of Example 78, step 2 to yield the final compound as a light-yellow solid, MS (ISP): m/e=343.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-a274873efb654f5fbccceb08f7987873 |
| Source note | uspto-grants-2008_08 |