2-Amino-4-methylthiazole → HCID 11659866, compound

HRID 2219574Notes

Reaction equation

HRID 2219574 reaction equation
C(O[C:4]([C:6]1[C:11]([NH:12][C:13]2[CH:14]=[N:15][CH:16]=[N:17][CH:18]=2)=[CH:10][CH:9]=[C:8]([CH3:19])[N:7]=1)=[O:5])C.[NH2:20][C:21]1[S:22][CH:23]=[C:24]([CH3:26])[N:25]=1>>[CH3:26][C:24]1[N:25]=[C:21]([NH:20][C:4]([C:6]2[C:11]([NH:12][C:13]3[CH:18]=[N:17][CH:16]=[N:15][CH:14]=3)=[CH:10][CH:9]=[C:8]([CH3:19])[N:7]=2)=[O:5])[S:22][CH:23]=1

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 58368053Ethyl 6-methyl-3-(5-pyrimidinylamino)-2-pyridinecarboxylate

Product 1

HCID 11659866HCID 11659866, compound

Procedure

The title compound, was prepared in accordance with the general method of Example 78, step 2 from 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid ethyl ester and 2-amino-4-methylthiazole to yield the final compound as an off-white solid, MS (ISP): m/e=327.1 (M+H+).

Sources & evidence

ORD record
ord-1cde8c89cf994677b5f1dcb0e9f075d5
Source dataset
uspto-grants-2008_08
Patent number
US07414060B2

Reaction notes

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