HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-methylthiazole → 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid (5-methyl-thiazol-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-methylthiazole | HCID 351770 | — |
| Reactant | Ethyl 6-methyl-3-(5-pyrimidinylamino)-2-pyridinecarboxylate | HCID 58368053 | — |
| Product | 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid (5-methyl-thiazol-2-yl)-amide | HCID 11645557 | — |
Reaction Steps
The title compound, was prepared in accordance with the general method of Example 78, step 2 from 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid ethyl ester and 2-Amino-5-methylthiazole to yield the final compound as a yellow crystalline solid, MS (ISP): m/e=327.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-7ae697cfa1834b36b5bfabdaade68666 |
| Source note | uspto-grants-2008_08 |