HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylaluminum → HCID 131726997, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Reactant | Ethyl 6-methyl-3-(5-pyrimidinylamino)-2-pyridinecarboxylate | HCID 58368053 | — |
| Reactant | HCID 131726998 | HCID 131726998 | — |
| Product | HCID 131726997 | HCID 131726997 | — |
Reaction Steps
The Al(Me)3-catalyzed reaction of 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid ethyl ester and 4-(tert-Butyl-dimethyl-silanyloxymethyl)-thiazol-2-ylamine (CAS [752241-92-2]; WO2004076420) in accordance with the general method of Example 78, step 2 yielded the title compound as an off-white solid, MS (ISP): m/e=457.3 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-9a8229392d694a2c8826d17cca34751c |
| Source note | uspto-grants-2008_08 |