huagongshe.com
HRID2219578

反应详情

EQUATION

反应方程式

HRID 2219578 的结构方程式

REACTANTS

反应物

3
结构：[CH3][Al]([CH3])[CH3]
HCID16682925

Aluminum, trimethyl-

C3H9Al

结构：CCOC(=O)c1nc(C)ccc1Nc1cncnc1
HCID58368053

Ethyl 6-methyl-3-(5-pyrimidinylamino)-2-pyridinecarboxylate

C13H14N4O2

结构：CC(C)(C)[SiH2]OC(C)(C)c1csc(N)n1
HCID131726998

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(Nc2cncnc2)c(C(=O)Nc2nc(C(C)(C)O[SiH2]C(C)(C)C)cs2)n1
HCID131726997

未命名化合物

PROCEDURE

实验过程

The Al(Me)3-catalyzed reaction of 6-Methyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid ethyl ester and 4-(tert-Butyl-dimethyl-silanyloxymethyl)-thiazol-2-ylamine (CAS [752241-92-2]; WO2004076420) in accordance with the general method of Example 78, step 2 yielded the title compound as an off-white solid, MS (ISP): m/e=457.3 (M+H+).