HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromopyrimidine → HCID 131727000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromopyrimidine | HCID 78344 | — |
| Reactant | HCID 131727001 | HCID 131727001 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 131727000 | HCID 131727000 | — |
Reaction Steps
Palladium catalysed arylation of 3-Amino-6-(tert-butyl-dimethyl-silanyloxymethyl)-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide with 5-Bromopyrimidine according to the general procedure described in example 4 step 4 yielded the title product as a light yellow solid, MS (ISP): m/e=457.3 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-558c67c699c749c28629f4097dbf1fe5 |
| Source note | uspto-grants-2008_08 |