HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrimidin-5-amine → HCID 58368048, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrimidin-5-amine | HCID 344373 | — |
| Reactant | Ethyl 3-bromo-6-cyclopropyl-2-pyridinecarboxylate | HCID 69235471 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 58368048 | HCID 58368048 | — |
Reaction Steps
Palladium catalysed arylation of 3-Bromo-6-cyclopropyl-pyridine-2-carboxylic acid ethyl ester with 5-Aminopyrimidine according to the general procedure described in example 78 step 3 yielded the title compound as a white solid, MS (ISP): m/e=273.3 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-b2ebd6fda760442dbc92bfbe949d0715 |
| Source note | uspto-grants-2008_08 |