HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromopyruvate → Ethyl 2-(cyclohexylamino)-1,3-thiazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromopyruvate | HCID 66144 | — |
| Reactant | Cyclohexylthiourea | HCID 1471603 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2-(cyclohexylamino)-1,3-thiazole-4-carboxylate | HCID 15053542 | — |
Reaction Steps
To a suspension of 0.25 g (1.6 mmol) of N-cyclohexylthiourea in 2.5 mL of ethanol was added 0.31 g of ethyl bromopyruvate. The reaction was heated at reflux for 17 hr then evaporated to leave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414067B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-1ece7cf5962542ee89cebc004f2801e4 |
| Source note | uspto-grants-2008_08 |