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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2219769Generated: October 31, 2026

Phosphate → L-Leucine

https://huagongshe.com/reaction/2219769

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphateHCID 1061—
ReactantN-(N-(N-(N-L-Tyrosylglycyl)glycyl)-L-phenylalanyl)-L-leucineHCID 461776—
ProductL-LeucineHCID 6106—

Reaction Steps

The degradation H-Tyr-Gly-Gly-Phe-Leu-OH (SEQ ID NO: 12) (˜1.8×10−4 M) in 50 MM phosphate buffer solutions of pH 7.4 containing carboxypeptidase A (1 U/ml) was studied as described above. The pseudo first-order rate constant for the degradation was estimated to 9.8×10−1 min−1 and the corresponding half-life calculated to 0.7 min as previously described.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07414107B2
Source datasetuspto-grants-2008_08
ORD IDord-1abf1ee2c5ed4728b0063d184b1aa5eb
Source noteuspto-grants-2008_08