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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2220080Generated: October 31, 2026

Hydrochloric Acid → 1-Isopropyl-4-(3-methanesulfonyl-phenyl)-piperidine

https://huagongshe.com/reaction/2220080

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-BromopropaneHCID 6358—
Reactant4-(3-(Methylsulfonyl)phenyl)piperidineHCID 12988957—
Product1-Isopropyl-4-(3-methanesulfonyl-phenyl)-piperidineHCID 22397843—

Reaction Steps

Beginning with 4-(3-methanesulfonyl-phenyl)piperidine and i-propylbromide: m.p. 220° C. (HCl); MS m/z (rel. intensity, 70 eV) 281 (M+, 4), 266 (bp), 187 (5), 129 (5), 115 (5)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07417043B2
Source datasetuspto-grants-2008_08
ORD IDord-f8c2f8b6e0ee44a8ac60001783f39070
Source noteuspto-grants-2008_08