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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2220082Generated: October 31, 2026

Hydrochloric Acid → 1-Isobutyl-4-(3-methanesulfonyl-phenyl)-piperidine

https://huagongshe.com/reaction/2220082

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1-Bromo-2-methylpropaneHCID 6555—
Reactant4-(3-(Methylsulfonyl)phenyl)piperidineHCID 12988957—
Product1-Isobutyl-4-(3-methanesulfonyl-phenyl)-piperidineHCID 12988958—

Reaction Steps

Beginning with 4-(3-methanesulfonyl-phenyl)piperidine and i-butylbromide; m.p. 212° C. (HCl); MS m/z (rel. intensity, 70 eV) 295 (M+, 1), 252 (80), 129 (40), 115 (50), 70 (bp)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07417043B2
Source datasetuspto-grants-2008_08
ORD IDord-5786d23dc9b849f7b824105994ff659b
Source noteuspto-grants-2008_08