Hydrazine → 2-Bromobenzohydrazide

HRID 2220216Notes

Reaction equation

HRID 2220216 reaction equation
[Br:1][C:2]1[CH:11]=[CH:10][CH:9]=[CH:8][C:3]=1[C:4](OC)=[O:5].[NH2:12][NH2:13]>CCO>[Br:1][C:2]1[CH:11]=[CH:10][CH:9]=[CH:8][C:3]=1[C:4]([NH:12][NH2:13])=[O:5]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 11894Methyl 2-bromobenzoate

Product 1

HCID 1014602-Bromobenzohydrazide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of methyl 2-bromobenzoate (1.0 g, 4.7 mmol) in EtOH (15 mL) was treated with hydrazine (0.18 mL, 5.6 mmol) and heated to reflux for 15 hours. The resulting solution was concentrated to a white powder (998 mg).

Workup

  1. temperatureheated
  2. temperatureto reflux for 15 hours
  3. concentrationThe resulting solution was concentrated to a white powder (998 mg)

Sources & evidence

ORD record
ord-06912a1921b247f1b6541797231ef7e6
Source dataset
uspto-grants-2008_08
Patent number
US07417040B2

Reaction notes

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