HRID2220248

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5003444

Sodium cyanotrihydroborate

CH3BNNa

HCID15719078

5-Aminoquinolin-2(1H)-one

C9H8N2O

结构：CC(C)(CC(O)(C=O)C(F)(F)F)c1cc(F)cc2c1OCC2

HCID44184989

5-Fluoro-2,3-dihydro-α-hydroxy-γ,γ-dimethyl-α-(trifluoromethyl)-7-benzofuranbutanal

C15H16F4O3

PRODUCTS

生成物

结构：CC(C)(CC(O)(CNc1cccc2[nH]c(=O)ccc12)C(F)(F)F)c1cc(F)cc2c1OCC2

HCID11712382

未命名化合物

PROCEDURE

实验过程

Analogously to Example 1, the corresponding imine is produced starting from 250 mg of 4-(2,3-dihydro-5-fluoro-7-benzofuranyl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentanal and 124 mg of 5-aminoquinolin-2[1H]-one. After reaction with sodium cyanoborohydride, the title compound is obtained.