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HRID2220249

反应详情

EQUATION

反应方程式

HRID 2220249 的结构方程式

REACTANTS

反应物

3
结构：[BH3-]C#N.[Na+]
HCID5003444

Sodium cyanotrihydroborate

CH3BNNa

结构：Cc1ccc2c(N)c(F)ccc2n1
HCID12896813

未命名化合物

结构：CC(C)(CC(O)(C=O)C(F)(F)F)c1cc(F)cc2c1OCC2
HCID44184989

5-Fluoro-2,3-dihydro-α-hydroxy-γ,γ-dimethyl-α-(trifluoromethyl)-7-benzofuranbutanal

C15H16F4O3

PRODUCTS

生成物

1
结构：Cc1ccc2c(NCC(O)(CC(C)(C)c3cc(F)cc4c3OCC4)C(F)(F)F)c(F)ccc2n1
HCID11705681

未命名化合物

PROCEDURE

实验过程

Analogously to Example 1, the corresponding imine is produced starting from 250 mg of 4-(2,3-dihydro-5-fluoro-7-benzofuranyl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentanal and 138 mg of 5-amino-6-fluoro-2-methylquinoline. After reaction with sodium cyanoborohydride, the title compound is obtained.