HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 1-(2-Bromoethoxy)-4-iodobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 4-Iodophenol | HCID 10894 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Product | 1-(2-Bromoethoxy)-4-iodobenzene | HCID 1905847 | — |
Reaction Steps
The mixture of 4-iodophenol (6.0 g), 1,2-dibromoethane (26 ml) and potassium carbonate (5.28 g) was refluxed for 3 hours. The mixture was evaporated under reduced pressure. The residue was purified by column chromatography on silica gel (hexane/ethyl acetate=6/1) to give 1-(2-bromoethoxy)-4-iodobenzene (6.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417060B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-438df0372305452ebf1db964cb700d8e |
| Source note | uspto-grants-2008_08 |