HCID 23655921, compound → HCID 23655159, compound

HRID 2220589Notes

Reaction equation

HRID 2220589 reaction equation
[CH2:1]([C:5]1[O:6][C:7]2[CH:13]=[C:12]([C:14]([O:16][CH3:17])=[O:15])[CH:11]=[CH:10][C:8]=2[CH:9]=1)[CH2:2][C:3]#[CH:4]>C(Cl)Cl>[CH3:17][O:16][C:14]([C:12]1[CH:11]=[CH:10][C:8]2[CH:9]=[C:5]([CH2:1][CH2:2][C:3]3[O:6][C:7]4[CH:13]=[C:12]([C:14]([O:16][CH3:17])=[O:15])[CH:11]=[CH:10][C:8]=4[CH:4]=3)[O:6][C:7]=2[CH:13]=1)=[O:15]

Participants

3

Reactant 1

HCID 23655921HCID 23655921, compound

Product 1

HCID 23655159HCID 23655159, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following the procedure described above for 95, 101 was prepared from 94 to 100 as a white solid (0.6 g, 24%): mp 175-177° C. (CH2Cl2). 1H NMR (DMSO-d6) δ8.04 (b, 2H), 7.83 (dd, J=8.2, 1.1 Hz, 2H), 7.65 (d, J=8.2 Hz, 2H), 6.83 (s, 2H), 3.87 (s, 6H), 3.33 (s, 4H). HPLC (method B) tR 9.16 min (100.00 area %). Anal. (C22H18O6) C, H.

Sources & evidence

ORD record
ord-b32510fade6e4262b20879edd33d2428
Source dataset
uspto-grants-2008_08
Patent number
US07417158B2

Reaction notes

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