Hydrochloric Acid → HCID 69203504, compound

Participants

Reaction Steps

Ethyl 4′-{2-[(R)-2-hydroxy-2-(4-hydroxy-3-methanesulfonylaminophenyl)ethylamino]ethoxy}-2′,6′-dimethylbiphenyl-4-carboxylate was dissolved in ethyl acetate (4.3 mL), and a 4 mol/L solution of hydrogen chloride in ethyl acetate (0.2 mL) was added dropwise to the ice-cooled solution with stirring. The reaction mixture was concentrated in vacuo, and the residue was diluted with diethyl ether. The insoluble material was collected by filtration to afford the title compound (0.173 g).

Provenance & Evidence