4-Methylbenzaldehyde → 4,4'-DIMETHYLBENZOIN

HRID 2220679Notes

Reaction equation

HRID 2220679 reaction equation
[CH3:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[C-]#N.[K+]>>[CH3:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]([CH:6]([C:5]2[CH:8]=[CH:9][C:2]([CH3:1])=[CH:3][CH:4]=2)[OH:7])=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 77254-MethylbenzaldehydeHCID 9032Potassium Cyanide

Product 1

HCID 2248484,4'-DIMETHYLBENZOIN

Procedure

250 g (2.08 mol) of p-methylbenzaldehyde were condensed with the aid of 30 g (0.46 mol) of KCN to give 4,4′-dimethylbenzoin according to a standard method (Organikum 18th edition (1990) 457). The crude product was used without further purification (yield, crude: found: C, 80.0%, H, 6.4%. calculated: 79.97%, H, 6.71%). The IR spectrum of 4,4′-dimethylbenzoin is shown in FIG. 8.

Sources & evidence

ORD record
ord-5a277a03f05e4e70ae8a830b47b119a4
Source dataset
uspto-grants-2008_08
Patent number
US07417247B2

Reaction notes

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