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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2220768Generated: October 30, 2026

Pyrazole → HCID 59773342, compound

https://huagongshe.com/reaction/2220768

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrazoleHCID 1048—
ReactantAcetyl chlorideHCID 6367—
Reactant4-Methyl-5-(2-chloro-benzoylamino)-1-(pyridine-2-yl)-pyrazole-3-carboxylic acid(2-oxo-5-phenyl-2,3-dihydro-1h-benzo[e][1,4]diazepin-3-yl)amideHCID 59812227—
ReactantHCID 178424381HCID 178424381—
ProductHCID 59773342HCID 59773342—

Reaction Steps

The pyrazole acid, prepared as described in Procedure 8 using compound 188 (Procedure 41) in place of compound 20 and acetyl chloride in place of compound 21, was coupled to 2-(3,4,5,6-tetrahydro-2H-[1,4′]bipyridin-4-yl)ethylamine (prepared as described in Procedure 14) using the method of Procedure 10.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07417152B2
Source datasetuspto-grants-2008_08
ORD IDord-7a33782ec3b64bee8fcb8511644061b1
Source noteuspto-grants-2008_08