Hydrochloric Acid → HCID 57422604, compound

HRID 2220811Notes

Reaction equation

HRID 2220811 reaction equation
[CH:1]1([C:6]([CH:8]([NH:13]C(=O)OC(C)(C)C)[CH:9]([CH3:12])[CH2:10][CH3:11])=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[ClH:21]>>[Cl-:21].[CH:1]1([C:6](=[O:7])[CH:8]([NH3+:13])[CH:9]([CH3:12])[CH2:10][CH3:11])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 21952981HCID 21952981, compound

Product 1

HCID 57422604HCID 57422604, compound

Procedure

4 (0.18 g, 0.63 mmol) was dissolved in 2 ml HCl (7 N in dioxane). After completion of the reaction the solvent was removed and the resulting oil was purified by column chromatography on silical gel using a chloroform/methanol/water gradient. The resulting oil was triturated with ether.

Workup

  1. customAfter completion of the reaction the solvent
  2. customwas removed
  3. customthe resulting oil was purified by column chromatography on silical gel
  4. customThe resulting oil was triturated with ether

Sources & evidence

ORD record
ord-5f226638af4a4721ae8f6021d80ee866
Source dataset
uspto-grants-2008_05
Patent number
US07368421B2

Reaction notes

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