HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(2-Methoxy-5-morpholinophenyl)thiourea | HCID 22015733 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine | HCID 11402861 | — |
Reaction Steps
(2-Methoxy-5-morpholin-4-yl-phenyl)-thiourea (5.0 g, 19 mmol) in chloroform (130 ml) are treated with bromine (960 μl) and the mixture refluxed for 18 hours. After removal of the volatile components in vacuo, the product is recrystallized from THF (2.8 g, 57%). MS: m/e=266 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07368446B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-e786addbec634e43abf164a5c72877ee |
| Source note | uspto-grants-2008_05 |