HCID 69045866, compound → HCID 68708273, compound

Participants

Reaction Conditions

Reaction Steps

To a mixture of 1-methyl-7-trityl-1,4,5,7-tetrahydro-1,6,7-triaza-as -indacene-2,3-dicarboxylic acid 2-tert-butyl ester 3-ethyl ester VI (2.4 mmol) in EtOH (60 mL), 2N HCl (6 mL) was added and the reaction was heated at 80° C. for 2 h. The solvent was evaporated and the residue was washed twice with DCM/hexane. The title product was obtained as a solid (98% yield). ESI (+) MS: m/z 246 (MH+). 1H NMR: 1.27 (t, 3H), 2.78 (t, 2H), 2.97 (dt, 2H), 3.74 (s, 3H), 4.18 (q, 2H), 7.32 (s, 1H), 7.82 (s, 1H).

Provenance & Evidence