HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxo-[1,4']bipiperidinyl-1'-carboxylic acid benzyl ester → [1,4'-Bipiperidin]-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxo-[1,4']bipiperidinyl-1'-carboxylic acid benzyl ester | HCID 23369980 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | [1,4'-Bipiperidin]-2-one | HCID 21839852 | — |
Reaction Steps
2-Oxo-[1,4′]bipiperidinyl-1′-carboxylic acid benzyl ester (2.5 g) and Pearlman's catalyst (0.50 g) was stirred in ethanol (30 mL) under hydrogen (1 atm). After 20 hours the reaction as filtered through celite and concentrated. The title compound was obtained as a white solid (1.45 g). MS: m/z=183 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07368461B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-cad510d22ef144e9bbc92fbeab35ec16 |
| Source note | uspto-grants-2008_05 |