Potassium Hydroxide → HCID 24989583, compound

Participants

Reaction Steps

To a solution of 4,5-dihydro-1H-pyrrolo[2,3-f]isoquinoline-3-carboxylic acid ethyl ester E2 (0.165 mmol) in ethanol (3 mL), 2N KOH (20 eq) was added and the mixture was heated at 60° for 4 h. After solvent removal the solution was neutralized with 1N HCl and the precipitate was filtered and dried, providing the title compound in 56% yield.

Provenance & Evidence