HCID 23089328, compound → HCID 86605945, compound

HRID 2222056Notes

Reaction equation

HRID 2222056 reaction equation
[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[C:8]([F:17])([F:16])[C:9]([F:15])([F:14])[S:10]([O-:13])(=[O:12])=[O:11].[Na+].CS([O-])(=O)=O.[CH2:24]([O:28][C:29]1[CH:30]=[C:31]2[C:36](=[CH:37][CH:38]=1)[CH:35]=[C:34]([S+:39]1[CH2:43][CH2:42][CH2:41][CH2:40]1)[CH:33]=[CH:32]2)[CH2:25][CH2:26][CH3:27]>ClCCl>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[C:8]([F:17])([F:16])[C:9]([F:14])([F:15])[S:10]([O-:13])(=[O:11])=[O:12].[CH2:24]([O:28][C:29]1[CH:30]=[C:31]2[C:36](=[CH:37][CH:38]=1)[CH:35]=[C:34]([S+:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1)[CH:33]=[CH:32]2)[CH2:25][CH2:26][CH3:27]

Participants

4

Reactant 2

HCID 23089328HCID 23089328, compoundHCID 59514422HCID 59514422, compound

Product 1

HCID 86605945HCID 86605945, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

100 ml of dichloromethane and 28.61 g of sodium 2-(bicyclo[2.2.1]heptan-2-yl)tetrafluoroethane sulfonate were added to the aqueous solution of 1-(6-n-butoxynaphthalen-2-yl)tetrahydrothiophenium methane sulfonate and the mixture was stirred for 12 hours. After removing the water layer using a separating funnel, the organic layer was washed five times with 40 ml of purified water. The solvent was evaporated using a rotary evaporator under reduced pressure by a stream aspirator at room temperature and the residue was dried at 50° C. under reduced pressure to obtain 24.2 g of 1-(6-n-butoxynaphthalen-2-yl)tetrahydrothiophenium 2-(bicyclo[2.2.1]heptan-2-yl)tetrafluoroethane sulfonate as a white solid.

Workup

  1. customAfter removing the water layer
  2. washthe organic layer was washed five times with 40 ml of purified water
  3. customThe solvent was evaporated
  4. customa rotary evaporator under reduced pressure by a stream aspirator at room temperature
  5. customthe residue was dried at 50° C. under reduced pressure

Sources & evidence

ORD record
ord-fb69a336d7514f069cc06904e682b8c7
Source dataset
uspto-grants-2008_05
Patent number
US07371503B2

Reaction notes

Loading…