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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2222128Generated: October 31, 2026

HCID 86603475, compound → HCID 11712998, compound

https://huagongshe.com/reaction/2222128

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86603475HCID 86603475—
ReactantHCID 178418361HCID 178418361—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
ProductHCID 11712998HCID 11712998—

Reaction Conditions

Temperature20 °C

Reaction Steps

33 mg (0.045 mmol) benzyl (3-{4-[4-((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydro-pteridin-2-ylamino)-3-methoxy-phenyl]-piperazin-1-yl}-propyl)-carbamate are taken up in 5 ml of methanol combined with 4 mg palladium hydroxide and stirred for 24 h at 20° C. and 7 bar hydrogen pressure. Then the catalyst is filtered off and the solvent is eliminated in vacuo.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07371753B2
Source datasetuspto-grants-2008_05
ORD IDord-117ebf5dde2f4cfd8580ccaefe2cde7d
Source noteuspto-grants-2008_05