HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloroquinoline-4-carbaldehyde → 6-Chloroquinoline-4-carbaldehyde [3-(cyclopropylmethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4yl]hydrazone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloroquinoline-4-carbaldehyde | HCID 3146031 | — |
| Reactant | 1-cyclopropylmethyl-6-hydrazinopyrimidine-2,4[1H,3H]dione | HCID 17990173 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-Chloroquinoline-4-carbaldehyde [3-(cyclopropylmethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4yl]hydrazone | HCID 68892759 | 105.1% |
Reaction Steps
To a suspension of 1-cyclopropylmethyl-6-hydrazinopyrimidine-2,4[1H,3H]dione (5.05 g) in methanol (75 mL) was added 6-chloroquinoline 4-carbaldehyde (5.30 g). After stirring overnight, the reaction was filtered, yielding a yellow solid (10 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07371757B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-aff998c262c049c99813a645d36b5400 |
| Source note | uspto-grants-2008_05 |