Acetic Anhydride → 4-[(Z)-2-cyano-2-(3,4-dimethoxy-phenyl)-vinyl]-phenyl acetate

HRID 2222323Notes

Reaction equation

HRID 2222323 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[C:11](=[CH:14]/[C:15]2[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=2)/[C:12]#[N:13])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[C:22](OC(=O)C)(=[O:24])[CH3:23]>N1C=CC=CC=1>[C:22]([O:21][C:18]1[CH:17]=[CH:16][C:15](/[CH:14]=[C:11](\[C:12]#[N:13])/[C:5]2[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=2)=[CH:20][CH:19]=1)(=[O:24])[CH3:23]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 10446442(Z)-2-(3,4-dimethoxyphenyl)-3-(4-hydroxyphenyl)acrylonitrile

Product 1

HCID 100418614-[(Z)-2-cyano-2-(3,4-dimethoxy-phenyl)-vinyl]-phenyl acetateYield 95%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Compound 1 (0.28 g) was acetylated with acetic anhydride and pyridine in accordance with a customary method, to thereby produce the target product (0.30 g, yield: 95%).

Sources & evidence

ORD record
ord-788f0c6197a040d0a957ac8da95c5ae1
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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