3,4-Dimethoxybenzeneacetonitrile → HCID 6273719, compound

HRID 2222335Notes

Reaction equation

HRID 2222335 reaction equation
[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[CH3:10][O:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][C:20]=1[O:21][CH3:22])[CH2:15][C:16]#[N:17]>>[Br:1][C:2]1[CH:9]=[CH:8][C:5](/[CH:6]=[C:15](/[C:14]2[CH:18]=[CH:19][C:20]([O:21][CH3:22])=[C:12]([O:11][CH3:10])[CH:13]=2)\[C:16]#[N:17])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 667273,4-DimethoxybenzeneacetonitrileHCID 707414-Bromobenzaldehyde

Product 1

HCID 6273719HCID 6273719, compoundYield 78.6%

Procedure

4-Bromobenzaldehyde (2.0 g) and 3,4-dimethoxybenzyl cyanide (1.9 g) were subjected to condensation in accordance with process A of (production process 2), to thereby produce the target product (2.9 g, yield: 78%).

Sources & evidence

ORD record
ord-e4080ae082744eeeb064f69c31d5b141
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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