4-Nitrobenzaldehyde → HCID 23089852, compound

HRID 2222340Notes

Reaction equation

HRID 2222340 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[CH2:17][C:18]#[N:19]>>[CH3:12][O:13][C:14]1[CH:15]=[C:16](/[C:17](=[CH:8]/[C:7]2[CH:10]=[CH:11][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)/[C:18]#[N:19])[CH:20]=[CH:21][C:22]=1[O:23][CH3:24]

Participants

3

Reactant 2

HCID 5414-NitrobenzaldehydeHCID 667273,4-Dimethoxybenzeneacetonitrile

Product 1

HCID 23089852HCID 23089852, compoundYield 85%

Procedure

4-Nitrobenzaldehyde (760 mg) and 3,4-dimethoxybenzyl cyanide (890 mg) were subjected to condensation in accordance with process B of (production process 2), to thereby produce the target product (1.31 g, yield: 85%).

Sources & evidence

ORD record
ord-4ca84015ff9342268b9afa526904b284
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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