4-Cyanobenzaldehyde → HCID 10401953, compound

HRID 2222342Notes

Reaction equation

HRID 2222342 reaction equation
[C:1]([C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1)#[N:2].[CH3:11][O:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[CH2:16][C:17]#[N:18]>>[C:17](/[C:16](/[C:15]1[CH:19]=[CH:20][C:21]([O:22][CH3:23])=[C:13]([O:12][CH3:11])[CH:14]=1)=[CH:7]\[C:6]1[CH:9]=[CH:10][C:3]([C:1]#[N:2])=[CH:4][CH:5]=1)#[N:18]

Participants

3

Reactant 2

HCID 660424-CyanobenzaldehydeHCID 667273,4-Dimethoxybenzeneacetonitrile

Product 1

HCID 10401953HCID 10401953, compoundYield 112.9%

Procedure

4-Cyanobenzaldehyde (1.97 g) and 3,4-dimethoxybenzyl cyanide (1.80 g) were subjected to condensation in accordance with process A of (production process 2), to thereby produce the target product (3.33 g, yield: 77%).

Sources & evidence

ORD record
ord-fe64c6483eb94fd58e5e0e8894760158
Source dataset
uspto-grants-2008_05
Patent number
US07371773B2

Reaction notes

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