HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 23089844, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 9995865 | HCID 9995865 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 23089844 | HCID 23089844 | 97% |
Reaction Steps
Compound 57 (500 mg) was suspended in hydrochloric acid (1.1 eq.), and 1,4-dioxane and acetonitrile were added to and dissolved in the resultant suspension. The resultant reaction mixture was concentrated to dryness under reduced pressure, followed by recrystallization, to thereby produce the target product (550 mg, yield: 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07371773B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-9ddcb8ed07464fa189b60ffd818a9775 |
| Source note | uspto-grants-2008_05 |