反应详情

温度

90 °C

A mixture of 1,2,3-triazole (5 g, 72.4 mmol) and ethyl acrylate (7.8 ml, 72.4 mmol) containing pyridine (50 drops) was heated at 90° C. for 4 hours. After cooling, the volatiles were removed under vacuum and the residue was purified by column chromatography eluting with methylene chloride/ether to give ethyl (1H-1,2,3-triazol-1-yl)propanoate (8.96 g, 73%).

1. temperatureAfter cooling
2. customthe volatiles were removed under vacuum
3. customthe residue was purified by column chromatography
4. washeluting with methylene chloride/ether