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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2222501Generated: October 31, 2026

5-Chlorovaleryl chloride → Methyl 4-(5-chloro-pentanoyl-amino)-3-methoxy-benzoate

https://huagongshe.com/reaction/2222501

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chlorovaleryl chlorideHCID 74089—
ReactantMethyl 4-amino-3-methoxybenzoateHCID 602411—
SolventTetrahydrofuranHCID 8028—
ProductMethyl 4-(5-chloro-pentanoyl-amino)-3-methoxy-benzoateHCID 67048137—

Reaction Steps

Prepared analogously to Example 6a from methyl 4-amino-3-methoxy-benzoate and 5-chloro-pentanoic acid chloride in THF with TEA.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07371743B2
Source datasetuspto-grants-2008_05
ORD IDord-7e7f19a420f44c469fbcb59bcf0f416c
Source noteuspto-grants-2008_05