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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2222534Generated: October 31, 2026

Water → 3-Methyl-4-(5-oxo-[1,4]oxazepan-4-yl)benzoic acid

https://huagongshe.com/reaction/2222534

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantLithium HydroxideHCID 3939—
ReactantMethyl 3-methyl-4-(5-oxo-[1,4]oxazepan-4-yl)-benzoateHCID 67048367—
SolventEthanolHCID 702—
Product3-Methyl-4-(5-oxo-[1,4]oxazepan-4-yl)benzoic acidHCID 67048325—

Reaction Steps

Prepared analogously to Example 39d from methyl 3-methyl-4-(5-oxo-[1,4]oxazepan-4-yl)-benzoate and lithium hydroxide in a solvent mixture of water and ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07371743B2
Source datasetuspto-grants-2008_05
ORD IDord-c8210b2c6ef948eeba022ab413e104c1
Source noteuspto-grants-2008_05