Water → 3-Methyl-4-(5-oxo-[1,4]oxazepan-4-yl)benzoic acid

HRID 2222534Notes

Reaction equation

HRID 2222534 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[N:12]1[C:18](=[O:19])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)[C:5]([O:7]C)=[O:6].[OH-].[Li+].O>C(O)C>[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[N:12]1[C:18](=[O:19])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)[C:5]([OH:7])=[O:6]

Participants

5

Reactant 3

HCID 962WaterHCID 3939Lithium HydroxideHCID 67048367Methyl 3-methyl-4-(5-oxo-[1,4]oxazepan-4-yl)-benzoate

Product 1

HCID 670483253-Methyl-4-(5-oxo-[1,4]oxazepan-4-yl)benzoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 39d from methyl 3-methyl-4-(5-oxo-[1,4]oxazepan-4-yl)-benzoate and lithium hydroxide in a solvent mixture of water and ethanol.

Sources & evidence

ORD record
ord-c8210b2c6ef948eeba022ab413e104c1
Source dataset
uspto-grants-2008_05
Patent number
US07371743B2

Reaction notes

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