HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2222544Generated: October 31, 2026
Hydrochloric Acid → 1-(5-chloro-1H-benzimidazol-2-yl)-1-phenyl-methylamine
https://huagongshe.com/reaction/2222544
Participants
| Role | Name | HCID | Charge |
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| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178474527 | HCID 178474527 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(5-chloro-1H-benzimidazol-2-yl)-1-phenyl-methylamine | HCID 43114467 | — |
Reaction Steps
1.34 g (4.47 mmol) N-acetyl-1-(5-chloro-1H-benzimidazol-2-yl)-1-phenyl-methylamine in 9 ml of ethanol are combined with 18 ml of conc. hydrochloric acid and heated to 50° C. for 2 days. The reaction mixture is evaporated down i. vac. and twice taken up in ethanol and evaporated down again.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07371743B2 |
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| Source dataset | uspto-grants-2008_05 |
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| ORD ID | ord-c31caa2950fc40fb86f8658893843333 |
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| Source note | uspto-grants-2008_05 |
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