Phthalimide potassium salt → HCID 69101686, compound

HRID 2222568Notes

Reaction equation

HRID 2222568 reaction equation
I[CH2:2][CH2:3][CH2:4][CH2:5][CH:6]=[CH:7][CH2:8][CH2:9][CH2:10][CH2:11]I.[C:13]1(=[O:23])[NH:17][C:16](=[O:18])[C:15]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]12.[K]>CC(C)=O>[C:13]1(=[O:23])[N:17]([CH2:2][CH2:3][CH2:4][CH2:5][CH:6]=[CH:7][CH2:8][CH2:9][CH2:10][CH2:11][N:17]2[C:16](=[O:18])[C:15]3=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]3[C:13]2=[O:23])[C:16](=[O:18])[C:15]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]12

Participants

4

Reactant 2

HCID 24194345Phthalimide potassium saltHCID 91605735HCID 91605735, compound

Product 1

HCID 69101686HCID 69101686, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The 1,10-Diiodo-dec-5-ene (1 equiv.) is dissolved in anhydrous acetone at ambient temperature followed by the addition of potassium phthalimide (4. equiv.). The reaction mixture is stirred until completion, washed with brine, dried over magnesium sulfate, and concentrated in vacuo. The crude product is purified via silica gel chromatography to afford 1,10-dipthalimido-dec-5-ene.

Workup

  1. washwashed with brine
  2. dry with materialdried over magnesium sulfate
  3. concentrationconcentrated in vacuo
  4. customThe crude product is purified via silica gel chromatography

Sources & evidence

ORD record
ord-863940e65bda474db777218e1e18dfc2
Source dataset
uspto-grants-2008_05
Patent number
US07371852B2

Reaction notes

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