Succinic anhydride → HCID 12615272, compound

HRID 2222724Notes

Reaction equation

HRID 2222724 reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[C:7]1(=[O:13])[O:12][C:10](=[O:11])[CH2:9][CH2:8]1.C(OCC)(=[O:16])C>>[O:4]1[CH2:5][CH2:6][N:1]([CH:8]([CH2:9][C:10]([OH:16])=[O:11])[C:7]([OH:12])=[O:13])[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 7922Succinic anhydrideHCID 8083MorpholineHCID 8857Ethyl Acetate

Product 1

HCID 12615272HCID 12615272, compound

Procedure

Morpholine (8.9 g) and succinic anhydride (10.1 g) were dissolved in ethyl acetate (50 mL) and refluxed for 2 hours, and then the solvent was evaporated to obtain a crude product of monomorpholinosuccinic acid. By using the resulting crude product and the 1,3-diacylglycerol compound, Compound 1A-4-1 was obtained in the same manner as that used for Compound 1A-1-3.

Workup

  1. temperaturerefluxed for 2 hours
  2. customthe solvent was evaporated

Sources & evidence

ORD record
ord-101e8e8819e04c95b60ff8f736f9b7cd
Source dataset
uspto-grants-2008_05
Patent number
US07371877B2

Reaction notes

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