HRID2222779

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3018793

Ethyl 7-chloro-2-oxoheptanoate

C9H15ClO3

HCID10197657

(+)-2,2-Dimethylcyclopropanecarboxamide

C6H11NO

结构：CCOC(=O)/C(=C/CCCCCl)NC(=O)[C@H]1CC1(C)C

HCID57734487

未命名化合物

PRODUCTS

生成物

$结构：CCOC(=O)/C(=C\CCCCCl)NC(=O)[C@H]1CC1(C)C$

HCID67298182

未命名化合物

收率 10.5%

PROCEDURE

实验过程

As described in European Patent No. 48301, 250 g of ethyl 7-chloro-2-oxoheptanoate and 141 g of (S)-2,2-dimethyl cyclopropanecarboxamid were reacted and concentrated. In result, 372.4 g of ethyl (Z)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-hepnoate (2) containing, by gas chromatography assay, 10.5% of ethyl (E)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate (3) was obtained.

WORKUP

后处理

concentrationconcentrated
customIn result