HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 7-chloro-2-oxoheptanoate → ethyl (E)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 7-chloro-2-oxoheptanoate | HCID 3018793 | — |
| Reactant | (S)-2,2-Dimethylcyclopropanecarboxamide | HCID 10197657 | — |
| Reactant | ethyl (Z)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate | HCID 57734487 | — |
| Product | ethyl (E)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate | HCID 67298182 | 10.5% |
Reaction Steps
As described in European Patent No. 48301, 250 g of ethyl 7-chloro-2-oxoheptanoate and 141 g of (S)-2,2-dimethyl cyclopropanecarboxamid were reacted and concentrated. In result, 372.4 g of ethyl (Z)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-hepnoate (2) containing, by gas chromatography assay, 10.5% of ethyl (E)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate (3) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07371897B1 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-7893dcc369ee4b42a2f14bfca804083c |
| Source note | uspto-grants-2008_05 |