HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 86606020, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | HCID 86606021 | HCID 86606021 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86606020 | HCID 86606020 | — |
Reaction Steps
500 ml of triethylamine are added to a solution of 236.9 g of 1 in 1.2 l of dichloromethane. With ice cooling, a solution of 83.6 ml of methanesulfonyl chloride in 200 ml of dichloromethane is added. The mixture is stirred at 5-100 for 30 minutes, the precipitated triethylamine hydrochloride is removed, and the product is subjected to conventional work-up, giving 2 as oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07371854B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-64b9b8c154eb46c386498122609c66ce |
| Source note | uspto-grants-2008_05 |