1-Bromo-3-methoxypropane → HCID 68799377, compound

Participants

Reaction Steps

Prepared as described in example 3 except that tert-butoxycarbonylamino-[4-(3-methoxy-propoxy)-phenyl]-acetic acid was used in place of tert-butoxycarbonylamino-(3-fluoro-4-methoxy-phenyl)-acetic acid in step 7. (R)-tert-Butoxycarbonylamino-[4-(3-methoxy-propoxy)-phenyl]-acetic acid was prepared in a manner similar to that described for the preparation of tert-butoxycarbonylamino-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-acetic acid in example 4 (o) except that 1-bromo-3-methoxy-propane was used in place of chloroethylpyrrolidine hydrochloride.

Provenance & Evidence