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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2223026Generated: November 1, 2026

Glycine → lysylglycine

https://huagongshe.com/reaction/2223026

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
Reactant2,5-Dioxopyrrolidin-1-yl N~2~,N~6~-bis(tert-butoxycarbonyl)-L-lysinateHCID 13875534—
ProductlysylglycineHCID 7022320—

Reaction Steps

Lys-Gly-Amp was synthesized by a similar method except the amino acid starting material was Boc-Lys(Boc)-OSu and the starting drug conjugate was Gly-Amp (see Gly-Amp synthesis).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07375083B2
Source datasetuspto-grants-2008_05
ORD IDord-fa47e09f15c04993b12e41a749d2bc73
Source noteuspto-grants-2008_05