Dichloromethane → HCID 58617365, compound

Participants

Reaction Steps

Compound I1, a mixture of 4-(5,5-dimethyl-cyclohex-1-enyl)-morpholine/4-(3,3-Dimethyl-cyclohex-1-enyl)-morpholine (3:1), (1.28 g, 6.55 mmol.) and 4-ethoxyphenyl isocyanate (1.20 g, 7.20 mmol.) in 32 mL of chloroform was stirred at room temperature for 20 h. Upon completion, 50 mL of dichloromethane was added and the resulting solution was washed with water twice and brine, dried over anhydrous sodium sulfate and concentrated. There was obtained 2.04 g of I2, which was used in next step without purification. MS (ESI+) 290 [M+H]+.

Provenance & Evidence