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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2223260Generated: October 25, 2026

Diethyl dimethylmalonate → N-(3,5-Difluoro-benzyl)-2,2-dimethyl-malonamic acid

https://huagongshe.com/reaction/2223260

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl dimethylmalonateHCID 15382—
ReactantN-(3,5-difluoro-benzyl)-2-methyl-malonamic acidHCID 21091473—
ProductN-(3,5-Difluoro-benzyl)-2,2-dimethyl-malonamic acidHCID 21091472—

Reaction Steps

N-(3,5-Difluoro-benzyl)-2,2-dimethyl-malonamic acid was prepared in analogy to N-(3,5-difluoro-benzyl)-2-methyl-malonamic acid (example 1) from diethyl 2,2-dimethyl-malonate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07375099B2
Source datasetuspto-grants-2008_05
ORD IDord-dcc234a4c7cd427c8f29a3619fa9d9ba
Source noteuspto-grants-2008_05