(Trifluoromethyl)trimethylsilane → HCID 137329875, compound

Participants

Reaction Steps

In the reaction with (trifluoromethyl)-trimethylsilane analogously to instructions 1.1, 200 mg of alcohol 16a yields 200 mg of the column-chromatographically stable trimethylsilyl ether 17a as a light yellow, viscous mass (GC-MS: m/z theor.: 720, pract.: 720). The latter is, without the reaction with tetrabutylammonium fluoride-trihydrate being performed, used in the next stage.

Provenance & Evidence