反应详情

Compound 17a-S (1.05 g, 5.4 mmol) and 3,4-dichloropenylethylamine (1.02 g, 0.8 ml, 5.4 mmol) were dissolved in 25 ml ethanol and refluxed for 12 hours. Then the solvent was evaporated and the residue recrystallized from ethylacetate-petroleum ether to give the product (1.02 g, 99% yield, m.p. 73-74° C.) as a white solid.

1. temperaturerefluxed for 12 hours
2. customThen the solvent was evaporated
3. customthe residue recrystallized from ethylacetate-petroleum ether