HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(4-Fluorophenyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68527358 | HCID 68527358 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 2-(4-Fluorophenyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine | HCID 62548084 | — |
Reaction Steps
Prepared in analogy to example E (b) from 1-[2-(4-fluoro-phenyl)-6,7-dihydro-4H-thiazolo[5,4]pyridin-5-yl]-ethanone and hydrochloric acid. Chromatography (SiO2; dichloromethane/methanol 95:5) yields the title compound as a yellowish solid. MS (m/e): 235.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07375226B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-c3d4a9a011834b56a10f2831d07f3dec |
| Source note | uspto-grants-2008_05 |